The Dom Pedro Palace is situated in a 21-floor building close to attractions such as the Praca Marques de Pombal, Baixa, Torre de Belem and the Muse Nacional de Arte Antiga. The rooms afford views of the River Tagus. The Lisbon International Airport is roughly four miles from the Dom Pedro Palace.

The rooms at the Dom Pedro Palace number over 263 in total and are appointed with luxury amenities. Included in each room are televisions with in-room movies, air-conditioning, Internet access, radios, desks, minibars, and in-room safes. All of the rooms are soundproofed.

Onsite at the Dom Pedro Palace one has access to two restaurants two bars and a lobby lounge. The hotel's guest services include car rental, express check-out, currency exchange, laundry and valet services, storage for guest luggage, parking for private cars and a business center. Families can take advantage of babysitting services. For business travelers, there is a fax and photocopy service available onsite. There is also shopping onsite.